CYCLOBENZAPRINE Drugs in Pregnancy and Lactation: Tenth Edition

No published reports of its use in human pregnancy have been located. CYCLOBENZAPRINE (sye kloe BEN za preen) treats muscle spasms. It works by relaxing your muscles, which reduces muscle stiffness. It belongs to a group can you take flexeril with norco of medications called muscle relaxants. Cyclobenzaprine does not directly act on the neuromuscular intersection or the muscle. It relieves muscle spasms through a central action, possibly at the brainstem level.

(Bateman 2014) Another showed that 6% of pregnant women admitted nonmedical use of opioid analgesics during pregnancy and opioid users had significantly higher rates of psychiatric comorbidities. Prescription drug abuse in women of childbearing age can have significant consequences including unprotected sex, domestic violence, and child abuse. Although prescription drug abuse may not affect parenting ability, it is intuitive that treatment and abstinence are preferred. Unfortunately, patients may be hesitant to disclose their addiction for fear of losing custody of their children. (Committee 2012) Universal screening with brief intervention and referral to treatment is currently recommended for all prenatal patients to improve maternal and fetal outcomes. In addition to the physiologic changes that occur in the mother during pregnancy, one must also consider the impact of pharmacotherapy in the developing fetus.

During pregnancy, the lady faces discomfort from muscle-related issues. Most women suffer pain in their calves during pregnancy. Flexeril use should be closely monitored in pregnant women and caution should be exercised before deciding to take the medication.

If cyclobenzaprine is required by the mother, it is not a reason to discontinue breastfeeding. Monitor the infant for (drowsiness, adequate weight gain, and developmental milestones), especially in neonates and preterm infants and when using combinations of sedating drugs. It helps women in treating muscle spasms and all other muscle-related issues. Muscle spasms and back pain are common while pregnant, and Flexeril (cyclobenzaprine) is a muscle relaxant. This drug has been shown to be excreted in rat milk and achieve concentrations in the milk which are 50% of those in the rat maternal plasma. As this drug is closely related to the tricyclic antidepressants, some of which are known to be excreted in human milk, use caution especially when other drugs that cause sedation are used simultaneously.

Pain in the Pregnant and Postpartum Patient

Do not take more or less of it or take it more often than prescribed by your doctor. Cyclobenzaprine is a prescription medication that can relieve muscle pain and stiffness. But it can also cause various side effects, including drowsiness, dizziness, and dry mouth. This infographic will discuss ways to manage the side effects of Cyclobenzaprine and explore some alternative therapies while breastfeeding that may be worth trying. The quantity of Flexeril in breast milk is minimal, and infants generally tolerate it well.

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Your doctor will decide whether Flexeril or any other medication is safe enough for you to take during pregnancy 1. Cyclobenzaprine acts on the central nervous system (CNS) to produce its effects to relax the muscles. The action on CNS also causes some of this medicine’s side effects. Cyclobenzaprine is available only with a doctor’s prescription. Flexeril is usually given in 10 mg tablets up to three times daily 1. It is generally not considered addictive, but it may have side effects such as sleepiness and dizziness.

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Cyclobenzaprine binds to the serotonin receptor and is a receptor antagonist that reduces muscle tone by decreasing the activity of descending serotonergic neurons. There is not enough material on the way cyclobenzaprine acts on the brain but it is considered a good prescription choice for serious, painful sprains and strains, or temporary pain around the skeletal muscles. Cyclobenzaprine is used short-term to treat muscle spasms. It is usually used along with rest and physical therapy.

• The standard cyclobenzaprine dosage depends on the medication’s type and whether the patient is an adult or a child.
• If amitriptyline is discontinued abruptly, dizziness, headache, nausea, and restlessness may occur.
• Systematic reviews and meta-analyses support using skeletal muscle relaxants for short-term relief of acute low back pain when nonsteroidal anti-inflammatory drugs or acetaminophen are not effective or tolerated.
• If appropriate, include a statement that the use of the drug is compatible with breast-feeding.

A Flexeril overdose can occur if too much of the drug is consumed. The standard cyclobenzaprine dosage depends on the medication’s type and whether the patient is an adult or a child. Flexeril is a pain reliever that is widely taken to relieve muscle spasms and improve motor abilities, sleep, and energy levels. As a result, the activity of Cyclobenzaprine (Flexeril), which depresses the Central Nervous System and causes these sensations, could be a reason for Flexeril misuse and addiction. To effectively administer treatment options, it’s important to understand Flexeril, its purpose, and relevant potential side effects.

Skeletal muscle relaxants are widely used in treating musculoskeletal conditions. However, evidence of their effectiveness consists mainly of studies with poor methodologic design. In addition, these drugs have not been proven to be superior to acetaminophen or nonsteroidal anti-inflammatory drugs for low back pain. Systematic reviews and meta-analyses support using skeletal muscle relaxants for short-term relief of acute low back pain when nonsteroidal anti-inflammatory drugs or acetaminophen are not effective or tolerated.

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Taking MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Avoid taking MAO inhibitors (isocarboxazid, linezolid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine) during treatment with this medication.